Offer hope to your chronic stroke survivors

The Vivistim System pairs Vagus Nerve Stimulation (VNS) with upper limb rehabilitation therapy, providing 2-3 times the improvement in arm and hand function compared with intense therapy alone.1

For the up to 60% of survivors suffering from persistent upper limb impairments at six months following stroke, Paired VNS therapy offers1:

  • Improvements in impairment, function and quality of life
  • Arm and hand improvements
  • Efficacy in survivors up to 10 years post-stroke


Benefits of Vivistim


2-3 times the improvement in arm & hand function1


98% patient satisfaction2


65% of subjects saw clinically meaningful improvement in ADLs2

VNS Induces Neuroplasticity

Image 1 neuromodulators-1

VNS activates the brain’s attention system by prompting the release of neuromodulators—acetylcholine, norepinephrine, serotonin.3

Image 2 pre-post neurons

These neuromodulators interact with the motor neurons being activated during rehab, facilitating lasting structural changes.

Image 3 3-6 fold plasticity

In preclinical stroke models, VNS combined with rehab enhanced plasticity of brain motor connections that was 3-6 fold greater than rehab without VNS.3

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Vivistim Paired VNS System Implant Diagram-Callout+Labels

The Process

  • 1. Outpatient Procedure

    The device is placed during a short outpatient procedure, typically by a Neurosurgeon or ENT Physician. The generator is placed under the skin of the chest and the lead is tunneled from the neck to the generator.

  • 2. In-Clinic Therapy

    The therapist uses a button to activate the neurostimulator repeatedly during rehab tasks. Most patients do not feel the stimulation.

  • 3. At-Home Therapy

    Patients can activate Vivistim at home during rehab or daily activities using a special magnet.

Ready to learn more?

Vivistim Product Manuals

Instructions for Use

MRI Safety Information