Reclaim
Recovery

Help chronic
ischemic stroke patients

What is Vivistim Therapy™?

Vivistim Therapy can help break through chronic stroke limitations through the principles of neuroplasticity.

Vivistim^® is the first FDA-approved neurostimulation device used in chronic ischemic stroke patients with moderate to severe arm impairment. It pairs vagus nerve stimulation (VNS) with upper extremity rehabilitation therapy and daily activities to help strengthen the brain connections needed to relearn motor tasks and increase neuroplasticity in the chronic stage.

Paired VNS™ prompts the release of specific neuromodulators
Improves the brain’s ability to relearn motor tasks
Works within the brain to help the body during OT/PT

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Boosting Therapy Results

Clinically Proven

2–3 times more hand and arm function compared to intense therapy alone¹

FDA Approved Breakthrough Device

Approved by the FDA as safe and effective treatment for upper limb recovery after an ischemic stroke³

High Satisfaction

98% of Vivistim users were satisfied with their therapy²

Lasting Results

Improvements in function and reduction in impairment^1,4

How Vivistim Works

Vivistim Therapy induces more neuroplasticity

Vagus nerve stimulation (VNS) activates the brain’s attention system by prompting the release of neuromodulators—acetylcholine, norepinephrine, serotonin.³
These neuromodulators interact with the motor neurons being activated during rehab
Works with high repetitions of salient, goal-driven tasks to induce motor learning.

Vivistim Therapy is Proven Effective Across Multiple Studies

VNS-REHAB Pivotal Study, triple-blind RCT

The Lancet | 2021

Significant improvements in impairment and function compared with intense rehabilitation alone.²
Crossover group matched VNS group outcomes once VNS was enabled.

Neurorehabilitation and Neural Repair | 2023

The effects of Paired VNS were consistent across subgroups, including age, severity, and time post stroke.⁵

Stroke | 2025

Individuals treated with Paired VNS maintained long-term improvements in impairment, activity, participation, and quality of life at one-year.
Paired VNS is an FDA-approved, valuable treatment option providing long-term benefits for individuals with chronic upper extremity limitations after stroke.

Vivistim Implant

Simple, outpatient procedure

The device is placed during a short outpatient procedure, typically by a neurosurgeon or other qualified implanting surgeon.
The generator is placed under the skin of the chest and the lead is tunneled from the neck to the generator.